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Phosphoramidite-Rhodium Complexes as Catalysts for the Asymmetric [2+2+2] Cycloaddition of Alkenyl Isocyanates and Alkynes

The discovery and development of the asymmetric rhodium-catalyzed [2+2+2] cycloaddition of alkenyl isocyanates and exogenous alkynes to form indolizinone and quinolizinone scaffolds is described. This methodology has been expanded to include substituted alkenes and dienes, a variety of sterically an...

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Detalhes bibliográficos
Main Authors: Friedman, Rebecca Keller, Oberg, Kevin M., Dalton, Derek M., Rovis, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899493/
https://ncbi.nlm.nih.gov/pubmed/20622923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1351/PAC-CON-09-12-09
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