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Enantioselective Synthesis of Indolizidines Bearing Quaternary Substituted Stereocenters via Rhodium-Catalyzed [2+2+2] Cycloaddition of Alkenyl Isocyanates and Terminal Alkynes
[Image: see text] An enantioselective synthesis of indolizidines bearing quaternary substituted stereocenters by way of a rhodium catalyzed [2+2+2] cycloaddition of substituted alkenyl isocyanates and terminal alkynes is described. The reaction provides lactam products using aliphatic alkynes, while...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747361/ https://ncbi.nlm.nih.gov/pubmed/18284249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol800086s |
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