Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion

BACKGROUND: Prohormone convertase 1 is involved in maturation of peptides. Rare mutations in gene PCSK1, encoding this enzyme, cause childhood obesity and abnormal glucose homeostasis with elevated proinsulin concentrations. Common single nucleotide polymorphisms (SNPs) within this gene, rs6232 and...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Heni, Martin, Haupt, Axel, Schäfer, Silke A, Ketterer, Caroline, Thamer, Claus, Machicao, Fausto, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898666/
https://ncbi.nlm.nih.gov/pubmed/20534142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-86
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