Glycemia Determines the Effect of Type 2 Diabetes Risk Genes on Insulin Secretion

OBJECTIVE: Several single nucleotide polymorphisms (SNPs) in diabetes risk genes reduce glucose- and/or incretin-induced insulin secretion. Here, we investigated interactions between glycemia and such diabetes risk polymorphisms. RESEARCH DESIGN AND METHODS: Insulin secretion was assessed by insulin...

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Bibliographic Details
Main Authors: Heni, Martin, Ketterer, Caroline, Thamer, Claus, Herzberg-Schäfer, Silke A., Guthoff, Martina, Stefan, Norbert, Machicao, Fausto, Staiger, Harald, Fritsche, Andreas, Häring, Hans-Ulrich
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2010
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992789/
https://ncbi.nlm.nih.gov/pubmed/20802253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0674
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