Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin

INTRODUCTION: Recent meta-analyses of genome-wide association studies revealed new genetic loci associated with fasting glycemia. For several of these loci, the mechanism of action in glucose homeostasis is unclear. The objective of the study was to establish metabolic phenotypes for these genetic v...

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Main Authors: Wagner, Robert, Dudziak, Katarzyna, Herzberg-Schäfer, Silke A., Machicao, Fausto, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161735/
https://ncbi.nlm.nih.gov/pubmed/21887289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023639
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