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Cdk1 Activity Is Required for Mitotic Activation of Aurora A during G(2)/M Transition of Human Cells

In mammalian cells entry into and progression through mitosis are regulated by multiple mitotic kinases. How mitotic kinases interact with each other and coordinately regulate mitosis remains to be fully understood. Here we employed a chemical biology approach using selective small molecule kinase i...

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主要な著者: Van Horn, Robert D., Chu, Shaoyou, Fan, Li, Yin, Tinggui, Du, Jian, Beckmann, Richard, Mader, Mary, Zhu, Guoxin, Toth, John, Blanchard, Kerry, Ye, Xiang S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898447/
https://ncbi.nlm.nih.gov/pubmed/20444701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.141010
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