Studies on the Catalytic Mechanism of a Glutamic Peptidase

Scytalidoglutamic peptidase (SGP) is the prototype of fungal glutamic peptidases that are characteristically pepstatin insensitive. These enzymes have a unique catalytic dyad comprised of Gln(53) and Glu(136) that activate a bound water molecule for nucleophilic attack on the carbonyl carbon atom of...

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Main Authors: Kondo, Márcia Y., Okamoto, Débora N., Santos, Jorge A. N., Juliano, Maria A., Oda, Kohei, Pillai, Bindu, James, Michael N. G., Juliano, Luiz, Gouvea, Iuri E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898410/
https://ncbi.nlm.nih.gov/pubmed/20442413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.122432
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