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MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance
We reported that gene-selective formation of facultative heterochromatin silences transcription of acute inflammatory genes during endotoxin (LPS) tolerance, according to function. We discovered that reversal of the epigenetically silenced transcription restored mRNA levels but not protein synthesis...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898346/ https://ncbi.nlm.nih.gov/pubmed/20435889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115063 |
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