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MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance

We reported that gene-selective formation of facultative heterochromatin silences transcription of acute inflammatory genes during endotoxin (LPS) tolerance, according to function. We discovered that reversal of the epigenetically silenced transcription restored mRNA levels but not protein synthesis...

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Hlavní autoři: El Gazzar, Mohamed, McCall, Charles E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898346/
https://ncbi.nlm.nih.gov/pubmed/20435889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115063
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