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MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance

We reported that gene-selective formation of facultative heterochromatin silences transcription of acute inflammatory genes during endotoxin (LPS) tolerance, according to function. We discovered that reversal of the epigenetically silenced transcription restored mRNA levels but not protein synthesis...

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Autori principali: El Gazzar, Mohamed, McCall, Charles E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898346/
https://ncbi.nlm.nih.gov/pubmed/20435889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115063
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