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MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance

We reported that gene-selective formation of facultative heterochromatin silences transcription of acute inflammatory genes during endotoxin (LPS) tolerance, according to function. We discovered that reversal of the epigenetically silenced transcription restored mRNA levels but not protein synthesis...

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Détails bibliographiques
Auteurs principaux: El Gazzar, Mohamed, McCall, Charles E.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898346/
https://ncbi.nlm.nih.gov/pubmed/20435889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115063
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