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Chromatin-Specific Remodeling by HMGB1 and Linker Histone H1 Silences Proinflammatory Genes during Endotoxin Tolerance
Epigenetic silencing of tumor necrosis factor alpha (TNF-α) and interleukin 1β (IL-1β) transcription occurs in blood leukocytes of animals and humans after the initiation of severe systemic inflammation (SSI). We previously reported that the epigenetic signature requires induction of NF-κB factor Re...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655606/ https://ncbi.nlm.nih.gov/pubmed/19158276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01862-08 |
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