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NAD(+)-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

Gene-selective epigenetic reprogramming and shifts in cellular bioenergetics develop when Toll-like receptors (TLR) recognize and respond to systemic life-threatening infections. Using a human monocyte cell model of endotoxin tolerance and human leukocytes from acute systemic inflammation with sepsi...

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Bibliografske podrobnosti
Main Authors: Liu, Tie Fu, Yoza, Barbara K., El Gazzar, Mohamed, Vachharajani, Vidula T., McCall, Charles E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058977/
https://ncbi.nlm.nih.gov/pubmed/21245135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.196790
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