A Small Molecule Inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with Selectively Reversible Thiol Reactivity

Endoplasmic reticulum oxidation 1 (ERO1) is a conserved eukaryotic flavin adenine nucleotide-containing enzyme that promotes disulfide bond formation by accepting electrons from reduced protein disulfide isomerase (PDI) and passing them on to molecular oxygen. Although disulfide bond formation is an...

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Detalhes bibliográficos
Main Authors: Blais, Jaime D., Chin, King-Tung, Zito, Ester, Zhang, Yuhong, Heldman, Nimrod, Harding, Heather P., Fass, Deborah, Thorpe, Colin, Ron, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898301/
https://ncbi.nlm.nih.gov/pubmed/20442408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126599
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