Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

Endoplasmic reticulum (ER) stress–induced apoptosis is involved in many diseases, but the mechanisms linking ER stress to apoptosis are incompletely understood. Based on roles for C/EPB homologous protein (CHOP) and ER calcium release in apoptosis, we hypothesized that apoptosis involves the activat...

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Detalhes bibliográficos
Main Authors: Li, Gang, Mongillo, Marco, Chin, King-Tung, Harding, Heather, Ron, David, Marks, Andrew R., Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753154/
https://ncbi.nlm.nih.gov/pubmed/19752026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904060
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