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The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

Prolonged activation of the endoplasmic reticulum (ER) stress pathway known as the Unfolded Protein Response (UPR) can lead to cell pathology and subsequent tissue dysfunction. There is now ample evidence that the UPR is chronically activated in atherosclerotic lesional cells, particularly advanced...

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Detalhes bibliográficos
Autor principal: Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951143/
https://ncbi.nlm.nih.gov/pubmed/20884885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.224766
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