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Role of Endoplasmic Reticulum Stress in Atherosclerosis and Diabetic Macrovascular Complications

Age-related changes in endoplasmic reticulum (ER) are associated with stress of this cell organelle. Unfolded protein response (UPR) is a normal physiological reaction of a cell in order to prevent accumulation of unfolded and misfolded proteins in the ER and improve the normal ER function. However,...

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Autors principals: Chistiakov, Dmitry A., Sobenin, Igor A., Orekhov, Alexander N., Bobryshev, Yuri V.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100367/
https://ncbi.nlm.nih.gov/pubmed/25061609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/610140
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