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Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders

Perturbations in the normal functions of the endoplasmic reticulum (ER) trigger a signaling network that coordinates adaptive and apoptotic responses. There is accumulating evidence implicating prolonged ER stress in the development and progression of many diseases, including neurodegeneration, athe...

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Detalhes bibliográficos
Main Authors: Ozcan, Lale, Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290993/
https://ncbi.nlm.nih.gov/pubmed/22248326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-043010-144749
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