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The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load

Two related ER oxidation 1 (ERO1) proteins, ERO1α and ERO1β, dynamically regulate the redox environment in the mammalian endoplasmic reticulum (ER). Redox changes in cysteine residues on intralumenal loops of calcium release and reuptake channels have been implicated in altered calcium release and r...

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Главные авторы: Chin, King-Tung, Kang, Guoxin, Qu, Jiaxiang, Gardner, Lawrence B., Coetzee, William A., Zito, Ester, Fishman, Glenn I., Ron, David
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136342/
https://ncbi.nlm.nih.gov/pubmed/21507899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-184622
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