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High-throughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCV-associated hepatocellular carcinoma

Methylation of promoter CpG islands has been associated with gene silencing and demonstrated to lead to chromosomal instability. Therefore, some postulate that aberrantly methylated CpG regions may be important bio-markers indicative of cancer development. In this study we used the Illumina GoldenGa...

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Bibliografski detalji
Glavni autori: Archer, Kellie J., Mas, Valeria R., Maluf, Daniel G., Fisher, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898187/
https://ncbi.nlm.nih.gov/pubmed/20165882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00438-010-0522-y
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