Methylation of the CpG Sites Only on the Sense Strand of the APC Gene Is Specific for Hepatocellular Carcinoma

Hypermethylation of the promoter of the tumor suppressor gene, adenomatous polyposis coli (APC), occurs in various malignancies, including hepatocellular carcinoma (HCC). However, reports on the specificity of the methylation of the APC gene for HCC have varied. To gain insight into how these variat...

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Hlavní autoři: Jain, Surbhi, Chang, Ting-Tsung, Hamilton, James P., Lin, Selena Y., Lin, Yih-Jyh, Evans, Alison A., Selaru, Florin M., Lin, Pin- Wen, Chen, Shun-Hua, Block, Timothy M., Hu, Chi-Tan, Song, Wei, Meltzer, Stephen J., Su, Ying-Hsiu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206845/
https://ncbi.nlm.nih.gov/pubmed/22073196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026799
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