Methylation of the CpG Sites Only on the Sense Strand of the APC Gene Is Specific for Hepatocellular Carcinoma

Hypermethylation of the promoter of the tumor suppressor gene, adenomatous polyposis coli (APC), occurs in various malignancies, including hepatocellular carcinoma (HCC). However, reports on the specificity of the methylation of the APC gene for HCC have varied. To gain insight into how these variat...

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Detalhes bibliográficos
Main Authors: Jain, Surbhi, Chang, Ting-Tsung, Hamilton, James P., Lin, Selena Y., Lin, Yih-Jyh, Evans, Alison A., Selaru, Florin M., Lin, Pin- Wen, Chen, Shun-Hua, Block, Timothy M., Hu, Chi-Tan, Song, Wei, Meltzer, Stephen J., Su, Ying-Hsiu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206845/
https://ncbi.nlm.nih.gov/pubmed/22073196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026799
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