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High-throughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCV-associated hepatocellular carcinoma

Methylation of promoter CpG islands has been associated with gene silencing and demonstrated to lead to chromosomal instability. Therefore, some postulate that aberrantly methylated CpG regions may be important bio-markers indicative of cancer development. In this study we used the Illumina GoldenGa...

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Detalhes bibliográficos
Main Authors: Archer, Kellie J., Mas, Valeria R., Maluf, Daniel G., Fisher, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898187/
https://ncbi.nlm.nih.gov/pubmed/20165882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00438-010-0522-y
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