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Substoichiometric inhibition of Aβ(1-40) aggregation by a tandem Aβ(40-1-Gly8-1-40) peptide
Aβ peptides aggregate to form insoluble and neurotoxic fibrils associated with Alzheimer's disease. Inhibition of the aggregation has been the subject of numerous studies. Here we describe a novel, substoichiometric inhibitor of Aβ(1-40) fibrillization as a tandem dimeric construct consisting o...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897963/ https://ncbi.nlm.nih.gov/pubmed/20515649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.05.144 |
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