A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization

BACKGROUND: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to understand the characteristics of individual GPCRs and their subtypes. Previous phylogenetic classifications were all bas...

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Main Authors: van der Horst, Eelke, Peironcely, Julio E, IJzerman, Adriaan P, Beukers, Margot W, Lane, Jonathan R, van Vlijmen, Herman WT, Emmerich, Michael TM, Okuno, Yasushi, Bender, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897831/
https://ncbi.nlm.nih.gov/pubmed/20537162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-316
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