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Virtual screening of GPCRs: An in silico chemogenomics approach
BACKGROUND: The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules in the transmembrane ligand-binding site is therefore a crucial step in the drug discovery process, which remain...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2553090/ https://ncbi.nlm.nih.gov/pubmed/18775075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-363 |
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