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Hydroacylation of 2-Butyne from the Alcohol or Aldehyde Oxidation Level via Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation

Under the conditions of ruthenium catalyzed transfer hydrogenation, 2-butyne couples to alcohols 1a–1j to deliver α,β-unsaturated ketones 3a–3j in good to excellent isolated yields with complete E-stereoselectivity. Under identical conditions, aldehydes 2a–2j couple to 2-butyne to provide an identic...

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Detalhes bibliográficos
Main Authors: Williams, Vanessa M., Leung, Joyce C., Patman, Ryan L., Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897757/
https://ncbi.nlm.nih.gov/pubmed/20613891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2009.03.068
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