Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection

Periodic outbreaks of highly pathogenic avian H5N1 influenza viruses and the current H1N1 pandemic highlight the need for a more detailed understanding of influenza virus pathogenesis. To investigate the host transcriptional response induced by pathogenic influenza viruses, we used a functional-geno...

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Main Authors: Cilloniz, Cristian, Pantin-Jackwood, Mary J., Ni, Chester, Goodman, Alan G., Peng, Xinxia, Proll, Sean C., Carter, Victoria S., Rosenzweig, Elizabeth R., Szretter, Kristy J., Katz, Jacqueline M., Korth, Marcus J., Swayne, David E., Tumpey, Terrence M., Katze, Michael G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897611/
https://ncbi.nlm.nih.gov/pubmed/20504916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00553-10
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