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H7N9 and Other Pathogenic Avian Influenza Viruses Elicit a Three-Pronged Transcriptomic Signature That Is Reminiscent of 1918 Influenza Virus and Is Associated with Lethal Outcome in Mice

Modulating the host response is a promising approach to treating influenza, caused by a virus whose pathogenesis is determined in part by the reaction it elicits within the host. Though the pathogenicity of emerging H7N9 influenza virus in several animal models has been reported, these studies have...

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Detalhes bibliográficos
Main Authors: Morrison, Juliet, Josset, Laurence, Tchitchek, Nicolas, Chang, Jean, Belser, Jessica A., Swayne, David E., Pantin-Jackwood, Mary J., Tumpey, Terrence M., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178843/
https://ncbi.nlm.nih.gov/pubmed/24991006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00570-14
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