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A Comparison of the Binding Sites of Matrix Metalloproteinases and Tumor Necrosis Factor-α Converting Enzyme: Implications for Selectivity

MMPs and TACE (ADAM-17) assume independent, parallel or opposite pathological roles in cancer, arthritis, and several other diseases. For therapeutic purposes, selective inhibition of individual MMPs and TACE is required in most cases due to distinct roles in diseases and the need to preserve activi...

詳細記述

保存先:
書誌詳細
主要な著者: Lukacova, Viera, Zhang, Yufen, Kroll, Daniel M., Raha, Soumyendu, Comez, Dogan, Balaz, Stefan
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896057/
https://ncbi.nlm.nih.gov/pubmed/15801829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0491703
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