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A Comparison of the Binding Sites of Matrix Metalloproteinases and Tumor Necrosis Factor-α Converting Enzyme: Implications for Selectivity

MMPs and TACE (ADAM-17) assume independent, parallel or opposite pathological roles in cancer, arthritis, and several other diseases. For therapeutic purposes, selective inhibition of individual MMPs and TACE is required in most cases due to distinct roles in diseases and the need to preserve activi...

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Bibliografski detalji
Glavni autori: Lukacova, Viera, Zhang, Yufen, Kroll, Daniel M., Raha, Soumyendu, Comez, Dogan, Balaz, Stefan
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896057/
https://ncbi.nlm.nih.gov/pubmed/15801829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0491703
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