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Structural Determinants of Binding of Aromates to Extracellular Matrix: A Multi-Species Multi-Mode CoMFA Study
For small molecules acting in tissues, including signaling peptides, effectors, inhibitors, and other drug candidates, nonspecific binding to the extracellular matrix (ECM) is a critical phenomenon affecting their disposition, toxicity, and other effects. A commercially available ECM mimic, forming...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896058/ https://ncbi.nlm.nih.gov/pubmed/17226922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060188l |
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