Binding of Matrix Metalloproteinase Inhibitors to Extracellular Matrix: 3D-QSAR Analysis

Binding to the extracellular matrix (ECM), one of the most abundant human protein complexes, significantly affects drug disposition. Specifically, the interactions with ECM determine the free concentrations of small molecules acting in tissues, including signaling peptides, inhibitors of tissue remo...

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Detalhes bibliográficos
Main Authors: Zhang, Yufen, Lukacova, Viera, Bartus, Vladimir, Nie, Xiaoping, Sun, Guorong, Manivannan, Ethirajan, Ghorpade, Sandeep R., Jin, Xiaomin, Manyem, Shankar, Sibi, Mukund P., Cook, Gregory R., Balaz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896061/
https://ncbi.nlm.nih.gov/pubmed/18844670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2008.00710.x
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