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HIV gp41 Engages gC1qR on CD4+ T Cells to Induce the Expression of an NK Ligand through the PIP3/H2O2 Pathway

CD4(+) T cell loss is central to HIV pathogenesis. In the initial weeks post-infection, the great majority of dying cells are uninfected CD4(+) T cells. We previously showed that the 3S motif of HIV-1 gp41 induces surface expression of NKp44L, a cellular ligand for an activating NK receptor, on unin...

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Detaylı Bibliyografya
Asıl Yazarlar: Fausther-Bovendo, Hugues, Vieillard, Vincent, Sagan, Sandrine, Bismuth, Georges, Debré, Patrice
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895652/
https://ncbi.nlm.nih.gov/pubmed/20617170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000975
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