Viremic HIV Infected Individuals with High CD4 T Cells and Functional Envelope Proteins Show Anti-gp41 Antibodies with Unique Specificity and Function

BACKGROUND: CD4 T-cell decay is variable among HIV-infected individuals. In exceptional cases, CD4 T-cell counts remain stable despite high plasma viremia. HIV envelope glycoprotein (Env) properties, namely tropism, fusion or the ability to induce the NK ligand NKp44L, or host factors that modulate...

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Hlavní autoři: Curriu, Marta, Fausther-Bovendo, Hughes, Pernas, María, Massanella, Marta, Carrillo, Jorge, Cabrera, Cecilia, López-Galíndez, Cecilio, Clotet, Bonaventura, Debré, Patrice, Vieillard, Vincent, Blanco, Julià
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270019/
https://ncbi.nlm.nih.gov/pubmed/22312424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030330
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