HIV-1 envelope glycoproteins isolated from Viremic Non-Progressor individuals are fully functional and cytopathic

In untreated HIV-1-infected individuals, viremia is positively associated with disease progression. However, some viremic non progressors (VNPs) individuals show paradoxical high CD4(+) T cell counts. HIV-1 envelope glycoprotein complex (Env) is a major cytopathic determinant in viral replication; t...

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izdano v:Sci Rep
Main Authors: Cabrera-Rodríguez, Romina, Hebmann, Veronique, Marfil, Silvia, Pernas, María, Marrero-Hernández, Sara, Cabrera, Cecilia, Urrea, Victor, Casado, Concepción, Olivares, Isabel, Márquez-Arce, Daniel, Pérez-Yanes, Silvia, Estévez-Herrera, Judith, Clotet, Bonaventura, Espert, Lucile, López-Galíndez, Cecilio, Biard-Piechaczyk, Martine, Valenzuela-Fernández, Agustín, Blanco, Julià
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447548/
https://ncbi.nlm.nih.gov/pubmed/30944395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42075-3
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