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A vaccine strategy against AIDS: An HIV gp41 peptide immunization prevents NKp44L expression and CD4(+) T cell depletion in SHIV-infected macaques
We previously showed that a gp41 peptide (3S) induces expression of a natural killer (NK) ligand (NKp44L) on CD4(+) T cells during HIV-1 infection and that those cells are highly sensitive to NK lysis. In HIV-infected patients, anti-3S antibodies are associated with the maintenance of CD4(+) T cell...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2542869/ https://ncbi.nlm.nih.gov/pubmed/18234855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711629105 |
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