Optimization of the EC26-2A4 Epitope in the gp41 Membrane Proximal External Region Targeted by Neutralizing Antibodies from an Elite Controller

The analysis of patient derived HIV neutralizing antibodies (nAbs) and their target epitopes in the viral envelope (Env) protein provides important basic information for vaccine design. In this study we optimized an epitope, EC26-2A4, that is targeted by neutralizing antibodies from an elite control...

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Vydáno v:AIDS Res Hum Retroviruses
Hlavní autoři: Ringel, Oliver, Müller, Karsten, Koch, Joachim, Brill, Boris, Wolf, Timo, Stephan, Christoph, Vieillard, Vincent, Debré, Patrice, Dietrich, Ursula
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2018
Témata:
Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899297/
https://ncbi.nlm.nih.gov/pubmed/29262692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2017.0250
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