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Effects of Cell Cycle Inhibitors on Tau Phosphorylation in N2aTau3R Cells

Neurofibrillary tangles are one of the pathologic hallmarks of Alzheimer's disease (AD). They are composed of paired helical filaments (PHF) containing hyperphosphorylated forms of tau. Hyperphosphorylation of certain tau sites favors its dissociation from the microtubules (MT), interfering wit...

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Autors principals: Conejero-Goldberg, Concepcion, Townsend, Kirk, Davies, Peter
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895557/
https://ncbi.nlm.nih.gov/pubmed/18278567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-008-9044-z
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