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MiR-26b, Upregulated in Alzheimer's Disease, Activates Cell Cycle Entry, Tau-Phosphorylation, and Apoptosis in Postmitotic Neurons

MicroRNA (miRNA) functions in the pathogenesis of major neurodegenerative diseases such as Alzheimer's disease (AD) are only beginning to emerge. We have observed significantly elevated levels of a specific miRNA, miR-26b, in the defined pathological areas of human postmortem brains, starting f...

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Bibliographische Detailangaben
Hauptverfasser: Absalon, Sabrina, Kochanek, Dawn M., Raghavan, Venkatesan, Krichevsky, Anna M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810537/
https://ncbi.nlm.nih.gov/pubmed/24027266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1327-13.2013
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