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Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways
BACKGROUND: Expression of active c-Abl in adult mouse forebrain neurons in the AblPP/tTA mice resulted in severe neurodegeneration, particularly in the CA1 region of the hippocampus. Neuronal loss was preceded and accompanied by substantial microgliosis and astrocytosis. In contrast, expression of c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488571/ https://ncbi.nlm.nih.gov/pubmed/22938163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-208 |
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