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Have Tumor Suppressor PDCD4 and its Counteragent Oncogenic miR-21 Gone Rogue?

A recent article suggests that the well known tumor suppressor PDCD4 also functions as a pro-inflammatory agent. The PDCD4 counteragent miR-21, a pro-oncogenic micro-RNA, is described as an anti-inflammatory agent. The authors of this research article provide evidence that mice lacking PDCD4 are pro...

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Detalhes bibliográficos
Main Authors: Young, Matthew R., Santhanam, Arti N., Yoshikawa, Noriko, Colburn, Nancy H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895370/
https://ncbi.nlm.nih.gov/pubmed/20368367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.10.2.5
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