Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

Avermectin and its analogues are produced by the actinomycete Streptomyces avermitilis and are widely used in the field of animal health, agriculture, and human health. Here we have adopted a practical approach to successfully improve avermectin production in an industrial overproducer. Transcriptio...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhuo, Ying, Zhang, Wenquan, Chen, Difei, Gao, Hong, Tao, Jun, Liu, Mei, Gou, Zhongxuan, Zhou, Xianlong, Ye, Bang-Ce, Zhang, Qing, Zhang, Siliang, Zhang, Li-Xin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895102/
https://ncbi.nlm.nih.gov/pubmed/20534557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006085107
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