Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis

BACKGROUND: Milbemycins, produced from Streptomyces hygroscopicus subsp. aureolacrimosus and Streptomyces bingchenggensis, are 16-membered macrolides that share structural similarity with avermectin produced from Streptomyces avermitilis. Milbemycins possess strong acaricidal, insecticidal, and anth...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Kim, Myoun-Su, Cho, Wan-Je, Song, Myoung Chong, Park, Seong-Whan, Kim, Kaeun, Kim, Eunji, Lee, Naryeong, Nam, Sang-Jip, Oh, Ki-Hoon, Yoon, Yeo Joon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240415/
https://ncbi.nlm.nih.gov/pubmed/28095865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0626-8
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