Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

Avermectin and its analogues are produced by the actinomycete Streptomyces avermitilis and are widely used in the field of animal health, agriculture, and human health. Here we have adopted a practical approach to successfully improve avermectin production in an industrial overproducer. Transcriptio...

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Bibliografiske detaljer
Main Authors: Zhuo, Ying, Zhang, Wenquan, Chen, Difei, Gao, Hong, Tao, Jun, Liu, Mei, Gou, Zhongxuan, Zhou, Xianlong, Ye, Bang-Ce, Zhang, Qing, Zhang, Siliang, Zhang, Li-Xin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895102/
https://ncbi.nlm.nih.gov/pubmed/20534557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006085107
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