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Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

Avermectin and its analogues are produced by the actinomycete Streptomyces avermitilis and are widely used in the field of animal health, agriculture, and human health. Here we have adopted a practical approach to successfully improve avermectin production in an industrial overproducer. Transcriptio...

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Autori principali: Zhuo, Ying, Zhang, Wenquan, Chen, Difei, Gao, Hong, Tao, Jun, Liu, Mei, Gou, Zhongxuan, Zhou, Xianlong, Ye, Bang-Ce, Zhang, Qing, Zhang, Siliang, Zhang, Li-Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895102/
https://ncbi.nlm.nih.gov/pubmed/20534557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006085107
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