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Targeting and Processing of Site-specific DNA Interstrand Crosslinks
DNA interstrand crosslinks (ICLs) are among the most cytotoxic types of DNA damage, and thus ICL-inducing agents such as cyclophosphamide, melphalan, cisplatin, psoralen and mitomycin C have been used clinically as anti-cancer drugs for decades. ICLs can also be formed endogenously as a consequence...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895014/ https://ncbi.nlm.nih.gov/pubmed/20196133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20557 |
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