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Enhanced neuronal RNAi in C. elegans using SID-1
We expressed SID-1, a transmembrane protein from Caenorhabditis elegans that is required for systemic RNAi, in C. elegans neurons. This expression increased the response of neurons to dsRNA delivered by feeding. Mutations in the lin-15b and lin-35 genes further enhanced this effect. Worms expressing...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894993/ https://ncbi.nlm.nih.gov/pubmed/20512143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1463 |
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