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Conditional Gene Expression and RNAi Using MEC-8-Dependent Splicing in C. elegans
We describe a method for conditional regulation of gene expression based on the processing of an intron cassette by a splicing factor. The RNA processing factor MEC-8 is necessary for the function of the Caenorhabditis elegans touch receptor neurons; mec-8 mutants are touch insensitive. We show here...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862115/ https://ncbi.nlm.nih.gov/pubmed/20364149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1445 |
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