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Conditional Gene Expression and RNAi Using MEC-8-Dependent Splicing in C. elegans

We describe a method for conditional regulation of gene expression based on the processing of an intron cassette by a splicing factor. The RNA processing factor MEC-8 is necessary for the function of the Caenorhabditis elegans touch receptor neurons; mec-8 mutants are touch insensitive. We show here...

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Bibliografski detalji
Glavni autori: Calixto, Andrea, Ma, Charles, Chalfie, Martin
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862115/
https://ncbi.nlm.nih.gov/pubmed/20364149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1445
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