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Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of PD-1
CD4(+)FoxP3(+) regulatory T cells (T(reg)) play a critical role in maintaining self tolerance and inhibiting autoimmune disease. Despite being a major focus of modern immunological investigation, many aspects of T(reg) biology remain unknown. In a screen for novel candidate genes involved in human T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894810/ https://ncbi.nlm.nih.gov/pubmed/20190142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903943 |
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