FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling

Fc receptor–like 4 (FcRL4) is expressed on the surface of a subset of memory B cells (MBCs) located at sites of invading pathogens in mucosal lymphoid tissues in healthy individuals. Recently, FcRL4(+) MBCs were shown to be greatly increased in number in the peripheral blood of HIV-infected viremic...

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Bibliografiske detaljer
Main Authors: Sohn, Hae Won, Krueger, Peter D., Davis, Randall S., Pierce, Susan K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236118/
https://ncbi.nlm.nih.gov/pubmed/21908428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-353102
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