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FcγRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation

These studies investigate how interactions between the BCR and FcγRIIB affect B lymphocyte stimulator (BLyS) recep-tor expression and signaling. Previous studies showed that BCR ligation up-regulates BLyS binding capacity in mature B cells, reflecting increased BLyS receptor levels. Here we show tha...

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Detalhes bibliográficos
Main Authors: Crowley, Jenni E., Stadanlick, Jason E., Cambier, John C., Cancro, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644074/
https://ncbi.nlm.nih.gov/pubmed/18791164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-138651
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